Halo-Ed: Molecular Genetics Tutorial (MolGenT)

DasSarma Lab

Halo-Ed Portal

Halo-Gen

HaloWeb

Halo-Ed Education & Outreach

Useful Web-Links

About MolGenT

The sun gives off UV radiation that can damage DNA by inducing the formation of bonds between adjacent thymine bases. This type of damage is called a thymine dimer and causes a bulge to appear in the double helix, obstructing the normal DNA replication process and resulting in changes or mutations in the DNA sequence. However, UV damage can be repaired by special repair enzymes, including an endonuclease that excises the region of DNA containing the thymine dimer. Once the dimer has been removed, DNA polymerase fills in the gap with fresh nucleotides and another enzyme called DNA ligase seals the new segment of DNA into the repaired strand.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

For Questions and Suggestions, contact the Halo-Ed Team

Inheritance

Evolutionary Tree

                  Eukaryotic Cells

Cell Cycle

Mitosis

Meiosis

                   Prokaryotic Cells

Binary Fission

Transformation

Conjugation

                     Viruses

                              Bacteriophages

                              Transduction

                             Animal Viruses

                     Model Organisms

DNA & Genes

Nucleotide Structure

Structure of DNA Bases

Base Pairing

Deoxyribose 5' & 3' Ends

Deoxyribonucleotides

DNA Structure

DNA Double Helix

DNA Replication

                    Errors in Replication

DNA Replication, Repair and Recombination

DNA Replication

                    Ladder

                    Helix

Repair of UV Damage

Homologous Recombination

DNA Supercoiling

Gene Expression

          DNA → RNA → Protein

Central Dogma

Genotype vs Phenotype

Phenotype

RNA and Protein Building Blocks

Structure of RNA Bases

Ribose

Ribonucleotides

Amino Acids

Acidic

Basic

Polar

Apolar

Transcription and RNA Processing

RNA Splicing

Translation

tRNA Charging

Genetic Code

Operon

Biotechnology Applications

Impact of Molecular Genetics

Molecular Cloning

PCR Amplification

Protein Expression

DNA Fingerprinting

Genetic Enhancement

Cloning of Animals

CRISPR

Genome Sequencing

Personalized Medicine

Bioremediation

Agriculture and GMOs

          Intellectual Property

MolGenT Test

Copyright © Shiladitya DasSarma