Halo-Ed: Molecular Genetics Tutorial (MolGenT)

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About MolGenT

DNA can break and rejoin in a process called recombination. When DNA molecules share a similar sequence, they are said to be homologous to one another. The mutual exchange of corresponding genetic material between two such DNA molecules is called homologous recombination. This process begins when one strand of each DNA helix breaks and partially invades the other molecule, forming an X-shaped structure known as a Holliday junction. Next, winding and unwinding of the DNA results in branch migration, or leftward movement of the Holliday junction. One strand of each interchanging DNA segment can then be nicked, or cut by an endonuclease enzyme, and joined to the opposite molecule to produce two recombinant DNA double helices. This separates, or resolves, the two DNA molecules and completes the homologous recombination process.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

For Questions and Suggestions, contact the Halo-Ed Team

Inheritance

Evolutionary Tree

                  Eukaryotic Cells

Cell Cycle

Mitosis

Meiosis

                   Prokaryotic Cells

Binary Fission

Transformation

Conjugation

                     Viruses

                              Bacteriophages

                              Transduction

                             Animal Viruses

                     Model Organisms

DNA & Genes

Nucleotide Structure

Structure of DNA Bases

Base Pairing

Deoxyribose 5' & 3' Ends

Deoxyribonucleotides

DNA Structure

DNA Double Helix

DNA Replication

                    Errors in Replication

DNA Replication, Repair and Recombination

DNA Replication

                    Ladder

                    Helix

Repair of UV Damage

Homologous Recombination

DNA Supercoiling

Gene Expression

          DNA → RNA → Protein

Central Dogma

Genotype vs Phenotype

Phenotype

RNA and Protein Building Blocks

Structure of RNA Bases

Ribose

Ribonucleotides

Amino Acids

Acidic

Basic

Polar

Apolar

Transcription and RNA Processing

RNA Splicing

Translation

tRNA Charging

Genetic Code

Operon

Biotechnology Applications

Impact of Molecular Genetics

Molecular Cloning

PCR Amplification

Protein Expression

DNA Fingerprinting

Genetic Enhancement

Cloning of Animals

CRISPR

Genome Sequencing

Personalized Medicine

Bioremediation

Agriculture and GMOs

          Intellectual Property

MolGenT Test

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